Brunger Lab Publications
Huynh NP, Gloss CC, Lorentz J, Tang R, Brunger JM, McAlinden A, Zhang B, Guilak F: Long non-coding RNA GRASLND enhances chondrogenesis via suppression of interferon type II signaling pathway. Elife 2020, 9.
Toda S, Brunger JM, Lim WA: Synthetic development: learning to program multicellular self-organization. Curr Opin Syst Biol 2019, 14:41–49.
Pferdehirt L, Ross AK, Brunger JM, Guilak F: A Synthetic Gene Circuit for Self-Regulating Delivery of Biologic Drugs in Engineered Tissues. Tissue Eng Part A 2019, 25:809–820.
Huynh NPT, Brunger JM, Gloss CC, Moutos FT, Gersbach CA, Guilak F: Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds. Tissue Eng Part A 2018, 24:1531–1544.
Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F: CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues. Arthritis Rheumatol 2017, 69:1111–1121.
Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F: Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs. Stem Cell Reports 2017, 333:1307–1311.
Farhang N, Brunger JM, Stover JD, Thakore PI, Lawrence B, Guilak F, Gersbach CA, Setton LA, Bowles RD: CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments. Tissue Eng Part A 2017, doi:10.1089/ten.TEA.2016.0441.
Adkar SS, Brunger JM, Willard VP, Wu C-L, Gersbach CA, Guilak F: Genome Engineering for Personalized Arthritis Therapeutics. Trends Mol Med 2017, 23:917–931.
Diekman BO, Thakore PI, O’Connor SK, Willard VP, Brunger JM, Christoforou N, Leong KW, Gersbach CA, Guilak F: Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. Tissue Eng Part A 2015, 21:1261–74.
Glass KA, Link JM, Brunger JM, Moutos FT, Gersbach CA, Guilak F: Tissue-engineered cartilage with inducible and tunable immunomodulatory properties. Biomaterials 2014, 35:5921–5931.
Brunger JM, Huynh NPT, Guenther CM, Perez-Pinera P, Moutos FT, Sanchez-Adams J, Gersbach CA, Guilak F: Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage. Proc Natl Acad Sci 2014, 111:E798–E806.
Francisco AT, Mancino RJ, Bowles RD, Brunger JM, Tainter DM, Chen Y-T, Richardson WJ, Guilak F, Setton LA: Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration. Biomaterials 2013, 34:7381–7388.
Perez-Pinera P, Ousterout DG, Brunger JM, Farin AM, Glass KA, Guilak F, Crawford GE, Hartemink AJ, Gersbach CA: Synergistic and tunable human gene activation by combinations of synthetic transcription factors. Nat Methods 2013, 10:239–242.
Abrahamsson CK, Yang F, Park H, Brunger JM, Valonen PK, Langer R, Welter JF, Caplan AI, Guilak F, Freed LE: Chondrogenesis and mineralization during in vitro culture of human mesenchymal stem cells on three-dimensional woven scaffolds. Tissue Eng Part A 2010, 16:3709–18.
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