Lee JC*, Walton BL*, Hamann CA*, Brunger JM. Synthetic regulation of multicellular systems for regenerative engineering. Curr Opin Biomed Eng 2020. DOI: 10.1016/j.cobme.2020.100252 *Equal contributions

Huynh NP, Gloss CC, Lorentz J, Tang R, Brunger JM, McAlinden A, Zhang B, Guilak F. Long non-coding RNA GRASLND enhances chondrogenesis via suppression of interferon type II signaling pathway. Elife 2020, 9.

Toda S, Brunger JM, Lim WA: Synthetic development: learning to program multicellular self-organization. Curr Opin Syst Biol 2019, 14:41–49.

Pferdehirt L, Ross AK, Brunger JM, Guilak F. A Synthetic Gene Circuit for Self-Regulating Delivery of Biologic Drugs in Engineered Tissues. Tissue Eng Part A 2019, 25:809–820.

Huynh NPT, Brunger JM, Gloss CC, Moutos FT, Gersbach CA, Guilak F. Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition  on 3D Woven Scaffolds. Tissue Eng Part A 2018, 24:1531–1544.

Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F. CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues. Arthritis Rheumatol 2017, 69:1111–1121.

Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F. Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs. Stem Cell Reports 2017, 333:1307–1311.

Farhang N, Brunger JM, Stover JD, Thakore PI, Lawrence B, Guilak F, Gersbach CA, Setton LA, Bowles RD. CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments. Tissue Eng Part A 2017, doi:10.1089/ten.TEA.2016.0441.

Adkar SS, Brunger JM, Willard VP, Wu C-L, Gersbach CA, Guilak F. Genome Engineering for Personalized Arthritis Therapeutics. Trends Mol Med 2017, 23:917–931.

Diekman BO, Thakore PI, O’Connor SK, Willard VP, Brunger JM, Christoforou N, Leong KW, Gersbach CA, Guilak F. Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. Tissue Eng Part A 2015, 21:1261–74.

Glass KA, Link JM, Brunger JM, Moutos FT, Gersbach CA, Guilak F. Tissue-engineered cartilage with inducible and tunable immunomodulatory properties. Biomaterials 2014, 35:5921–5931.

Brunger JM, Huynh NPT, Guenther CM, Perez-Pinera P, Moutos FT, Sanchez-Adams J, Gersbach CA, Guilak F. Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage. Proc Natl Acad Sci 2014, 111:E798–E806.

Francisco AT, Mancino RJ, Bowles RD, Brunger JM, Tainter DM, Chen Y-T, Richardson WJ, Guilak F, Setton LA. Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration. Biomaterials 2013, 34:7381–7388.

Perez-Pinera P, Ousterout DG, Brunger JM, Farin AM, Glass KA, Guilak F, Crawford GE, Hartemink AJ, Gersbach CA. Synergistic and tunable human gene activation by combinations of synthetic transcription factors. Nat Methods 2013, 10:239–242.

Abrahamsson CK, Yang F, Park H, Brunger JM, Valonen PK, Langer R, Welter JF, Caplan AI, Guilak F, Freed LE. Chondrogenesis and mineralization during in vitro culture of human mesenchymal stem cells on three-dimensional woven scaffolds. Tissue Eng Part A 2010, 16:3709–18.

© Brunger Lab | Department of Biomedical Engineering | Vanderbilt University

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